نتایج جستجو برای: Ocular drug delivery

تعداد نتایج: 799878  

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده علوم پایه 1391

one of the applications of nanotechnology is use of carbon nanotubes for the targeted delivery of drug molecules. to demonstrate the physical and chemical properties of biomolecules and identify new material of drug properties, the interaction of carbon nanotubes (cnts) with biomolecules is a subject of many investigations. cnts is a synthetic compound with extraordinary mechanical, thermal, el...

Background: Tolmetin (Tol) is a pyrrole acetic acid derivative that acts as a highly effective topical anti-inflammatory agent. Topical administration of Tol is effective for the management of ocular inflammations.The aim of this study was to formulate and improve a topical ophthalmic delivery system of Tol. Materials and methods: In the present study, ocular inserts of Tol were prepared using ...

Journal: :The AAPS Journal 2010

Background: Tolmetin (Tol) is a pyrrole acetic acid derivative that acts as a highly effective topical anti-inflammatory agent. Topical administration of Tol is effective for the management of ocular inflammations.The aim of this study was to formulate and improve a topical ophthalmic delivery system of Tol. Materials and methods: In the present study, ocular inserts of Tol were prepared using ...

صادقی, محمدصالح , محمدپور, مهرداد ,

Eyes and the vision system allow the human being to receive information from the environment to the extent that 90% of the man’s information is acquired through observation, thus health and correct function of this organ have always been important. Diseases threatening vision such as Acute Macular Degeneration and Diabetic Retinopathy deprive millions of people of seeing every year while acce...

2015

Ocular drug delivery research acceleratedly advanced towards. Ocular drug delivery necessitates and helps drug delivery scientists to. Urgent need to develop ocular drug delivery systems which provide controlled. Pdflucentis-prescribing.pdf accessed on 18 October 2010. Delivery system, therefore, desires an integrated knowledge of the drug molecule and the restrictions offered by the ocular rou...

Journal: :World journal of pharmacology 2013
Ashaben Patel Kishore Cholkar Vibhuti Agrahari Ashim K Mitra

The major challenge faced by today's pharmacologist and formulation scientist is ocular drug delivery. Topical eye drop is the most convenient and patient compliant route of drug administration, especially for the treatment of anterior segment diseases. Delivery of drugs to the targeted ocular tissues is restricted by various precorneal, dynamic and static ocular barriers. Also, therapeutic dru...

2012
MEETALI MUDGIL NIDHI GUPTA MANJU NAGPAL PRAVIN PAWAR

In current drug delivery scenario, despite numerous scientific efforts, efficient ocular drug delivery remains a challenge for pharmaceutical scientists. In ocular drug delivery system, ocular infections are treated by various topical drug applications in the form of solutions, suspensions and ointment. These conventional dosage forms suffer from the problems of poor ocular bioavailability due ...

Journal: :Journal of Biomolecular Research & Therapeutics 2014

A.M. Godbole, S.A. Sreenivas, S.P. Hiremath,

In developing a drug delivery strategy, issues of absorption, distribution, metabolism, and elimination must be considered. The eye presents unique opportunities and challenges when it comes to the delivery of pharmaceuticals. While absorption by this route is bungling, there are few side effects with conventional ocular dosage forms. Hence, ocular inserts were prepared with prolonged release o...

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